[BioC] MEDIPS rms normalization by input
Herve Acloque [guest]
guest at bioconductor.org
Fri Oct 25 11:31:21 CEST 2013
I'm actually using MEDIPS to perform genome-wide methylation profile in satellite cells from normal animals. I have got a question regarding the way to normalize experimental rms regarding input rms. Is it possible to substract rms input score from the corresponding rms experimental condition? I was wondering whether it could be better to perform a differential coverage between experimental and input conditions and to keep only DMR regions.
Thank you for your help
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