[BioC] what is the difference between org.Hs.eg.dbGO2EG and org.Hs.eg.dbGO2ALLEGS?

Marc Carlson mcarlson at fhcrc.org
Fri Apr 11 01:57:03 CEST 2014

Hi Zhishi,

GO2EG doesn't choose terms.  It is the starting annotation. Somewhere 
someone decided that certain GO terms describes certain gene products 
and GO2EG is the direct result of that.  GO2ALLEGs is derived from 
GO2EG.  It starts with GO2EG and then appends all the implicit GO terms 
(based on relationships in the GO DAG hierarchy).

Does that clarify things?


On 04/09/2014 01:01 PM, Zhishi Wang wrote:
> Hi list,
> I have a question about the difference between org.Hs.eg.dbGO2EG and org.Hs.eg.dbGO2ALLEGS. The user manual of org.Hs.eg.db says that GO2EG does not associate the child terms from the GO ontology with the gene. Only the directly evidenced terms are represented in GO2EG. But, for example, ‘GO:0000435’, which is in GO2EG, has three parents: GO:0000431, GO:0000411, GO:0000436. None of the three parents is in GO2EG (they are all included in GO2ALLEGS). So this is conflicted with the description given in the manual?
> I want to know exactly how GO2EG choose terms. Thank you.
> Kind regards,
> Zhishi Wang
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