[BioC] Fwd: WGCNA: labeledHeatmap and verboseScatterplot correlations and p-values are not the same

Peter Langfelder peter.langfelder at gmail.com
Tue Aug 12 00:43:17 CEST 2014

On Mon, Aug 11, 2014 at 3:11 PM, Sindre Lee <sindre.lee at medisin.uio.no> wrote:
> I have to re-think what my approach should be then. I want to find
> weight-related genes and then find out how my intervention effects weight
> through these genes.

You may want to speak to a local statistician who can offer better
advice than me over email.

> So if I want to answer the question "Which genes are changed during
> intervention and associated the change in weight?", what would you suggest
> as an approach?

I don't know what your experimental design is, what are the controls -
is it time 1, or is time 1 baseline, time 2 after treatment, and you
have cases and controls? Are you interested in genes that relate to
weight in general, or genes whose change with respect to intervention
relates to change in weight with respect to intervention (you seem to
indicate both in what you wrote but they are two different questions)?


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