[BioC] Limma package and minimal number of genes

Ryan rct at thompsonclan.org
Wed Jun 11 03:41:33 CEST 2014


I believe Gordon has stated in the past that limma can be used with as 
few as 4 genes.


On Tue Jun 10 01:34:08 2014, Bas van Gestel wrote:
> Dear all,
> Currently, I'm comparing the gene expression of three cell types to
> identify differentially expressed genes. For this purpose, the limma
> package seems ideal. However, for one of the analyses, I would like to
> focus only on the transcription factors of the cell types. This implies
> that I only consider about 990 genes. Is this enough to perform an analysis
> with limma, or does it require a larger number of genes at minimum to give
> reliable results?
> Kind regards,
> Bas van Gestel
> 	[[alternative HTML version deleted]]
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