[R] RE: dna library

Matthew Nelson MattN at esperion.com
Fri Mar 24 12:56:11 CET 2000


Jim,

Thanks for making this library available.  As a trained human geneticist,
but a pharmaceutical scientist who spends most of my time working on
non-genetics projects using S-Plus/RWin/R (Linux), I've often thought that
it would be nice to stick with the same set of tools when I put my
geneticist/bioinformaticist hat back on.  In fact, I will often reformat
various genetics/DNA data sets for analysis in R.

Having said that, I would be happy to contribute to further development of
the library.  I will look for opportunities to use it and pass bug-reports
along to you.  I will also consider ways that it could be enhanced.  If
there are other ways that you feel I could contribute, please let me know.
I have five years of experience programming at various levels in S/R, and am
comfortable coding in C/C++.

Regards,

Matt

Matthew R. Nelson, Ph.D.
Information Scientist
Esperion Therapeutics, Inc.
3621 S. State St.
695 KMS Place
Ann Arbor, MI 48108

Phone: (734) 332-0506 x235
Fax: (734) 332-0516
email: mnelson at esperion.com
web: http://www.esperion.com
-----Original Message-----
From: Jim Lindsey [mailto:jlindsey at alpha.luc.ac.be]
Sent: Thursday, March 23, 2000 12:44 PM
To: r-announce at stat.math.ethz.ch
Subject: dna library



I have just placed version 0.2 alpha of my library, dna, on my web
page at
www.luc.ac.be/~jlindsey/rcode.html
The R functions in this library cover most of the basic methods of
dna and protein sequence analysis. The library includes ports of
CLUSTAL W for multiple sequence alignment and flip for finding open
reading frames in a dna sequence.
  There are an enormous number of interesting and challenging
statistical problems in current molecular biology and I am hoping that
making these procedures available to the R community will encourage
people to get involved.
  Some links to useful sites for learning about molecular biology can
be found at
www.luc.ac.be/~jlindsey/url.html
  Comments and suggestions for further inclusions in the library are
very welcome.
  Jim


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