[R] Using R for microarrays datas analysis by Mixed model ANOVA. lme function.
spencer.graves at pdf.com
Thu Sep 11 22:05:31 CEST 2003
1. Have you consulted Pinhiero and Bates (2000) Mixed-Effects Models in
S and S-Plus (Springer)? This is the standard (almost indispensible)
reference on "lme".
2. Are you familiar with the Bioconductor project
(www.bioconductor.org)? The have a substantial library of software for
analyzing microarray data.
hope this helps. spencer graves
Daphne Autran wrote:
> We are using R to analyse microarrays datas by ANOVA.
> We would like to set up Mixed Model analysis, using the "lme" function
> within the nmle package.
> However, we have problem in understanding and getting the right formula to
> build a "groupedData" object which appear to be required for lme to work.
> I ve read all the available nmle package s Users guides and manuals, but
> explications are scarce.
> Does anybody have an experience in using this function for microarrays datas
> analysis and could send me informations or, if possible, a resolved exemple
> (input table of datas, formula of the model, ouput...) ?
> Maybe other R functions are usefull and easier to implement Mixed Models
> ANOVA for microarrays analysis, any suggestions ?
> I thank you in advance for your reply.
> Daphne Autran
> Dr Daphne Autran
> Laboratory of Reproductive Development and Apomixis
> Department of Genetic Ingeniering
> CINVESTAV - Unidad Irapuato
> Km 9,6 Libramiento Norte
> C.P. 36500 Irapuato Guanajuato
> Tel : (0052) 462 623 9600 ext.404
> Fax : (0052) 462 624 5849
> Email : dautran at ira.cinvestav.mx
> R-help at stat.math.ethz.ch mailing list
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