[R] Repeated measures

[F Z]

5,000 repeated measures! You might have problems fitting a "old school" 
univariate or multivariate ANOVA RM model.  Can you group some of the 
measurements or you actually want to make inferences at each time point?  
Anyway, try using a newer method, like lme from the library lme4.  The book 
by Pinheiro and Bates "Mixed-Effects Models in S and S-Plus" describes 
several examples of RM analysis using their package.

Good luck!

Francisco


>From: Sean Davis <sdavis2 at mail.nih.gov>
>To: r-help <r-help at stat.math.ethz.ch>
>Subject: [R] Repeated measures
>Date: Wed, 6 Oct 2004 08:07:38 -0400
>
>I have a data set in which I have 5000 repeated measures on 6 subjects over 
>time (varying intervals, but measurements for all individuals are at the 
>same times).  There are two states, a "resting" state (the majority of the 
>time), and a perturbed state.  I have a continuous measurement at each time 
>point for each of the individuals.  I would like to determine the "state" 
>for each individual at each time point.  It looks to me like I should be 
>able to do this with the "hidden" command from the "repeated" package 
>(http://popgen0146uns50.unimaas.nl/~jlindsey/rcode.html), but I have found 
>it a bit confusing to get started.  The distributions in the two states are 
>approximately normal with differences in centrality and possibly variance 
>(but I can start by assuming similar variances).
>
>Thanks,
>Sean
>
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