[R] calculating IC50

Christian Ritz ritz at bioassay.dk
Thu Feb 2 15:39:04 CET 2006


Hi!

Yes, the 'drc' package can be used to obtain IC50 or any other ICx value 
for several, commonly used dose-response models.

The vignette is more up-to-date than the article in JSS (which dates 
back to the start of 2005).

Christian


Liaw, Andy wrote:

>Perhaps also of interest is the `drc' package on CRAN.  There's an article
>in JSS describing it (probably the same as the package vignette--- haven't
>checked).
>
>Andy
>
>From: Prof Brian Ripley
>  
>
>>On Thu, 2 Feb 2006 Arne.Muller at sanofi-aventis.com wrote:
>>
>>    
>>
>>>I was wondering if there is an R-package to automatically 
>>>      
>>>
>>calculate the 
>>    
>>
>>>IC50 value (concentration of a substrance that inhibits 
>>>      
>>>
>>cell growth to 
>>    
>>
>>>50%) for some measurements.
>>>      
>>>
>>Function dose.p in recommended package MASS.
>>
>>-- 
>>Brian D. Ripley,                  ripley at stats.ox.ac.uk
>>Professor of Applied Statistics,  http://www.stats.ox.ac.uk/~ripley/
>>University of Oxford,             Tel:  +44 1865 272861 (self)
>>1 South Parks Road,                     +44 1865 272866 (PA)
>>Oxford OX1 3TG, UK                Fax:  +44 1865 272595
>>
>>______________________________________________
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>>
>>    
>>
>
>______________________________________________
>R-help at stat.math.ethz.ch mailing list
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>
>  
>




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