[R] a question related to clustering

[Berton Gunter]

Sounds like you should go to the Bioconductor website
http://www.bioconductor.org/ and get plugged into their extensive and
professionally written software instead of shaking and baking your own.

-- Bert Gunter
Genentech Non-Clinical Statistics
South San Francisco, CA
 
"The business of the statistician is to catalyze the scientific learning
process."  - George E. P. Box
 
 

> -----Original Message-----
> From: r-help-bounces at stat.math.ethz.ch 
> [mailto:r-help-bounces at stat.math.ethz.ch] On Behalf Of Li, 
> Aiguo (NIH/NCI) [C]
> Sent: Wednesday, March 22, 2006 2:16 PM
> To: r-help at stat.math.ethz.ch
> Subject: [R] a question related to clustering
> 
> Hello all,
> 
>  
> 
> I have a fundamental question to ask related to clustering.  As you
> know, when we do statistic analysis, such as t-test, or anova, we like
> to log transform our data to make it normally distributed.  
> My question
> is shall we use signal intensity of affy chips to cluster or use log
> transformed data.  The Dendrogram profiles are certainly 
> different when
> comparing two type of the data.
> 
>  
> 
> Thanks,
> 
>  
> 
> AG
> 
> 
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> 
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