[R] time-dependent covariate survival curves

[Joel Dubin]

    Dear Hua,

    One approach:  use the function event.history in the Hmisc library.  
A citation for a 2001 Statistics in Medicine paper (Dubin, Muller, Wang) 
describing the method for plotting survival data with time-dependent 
covariates is contained in the help file.

    Good luck, Joel.


Joel Dubin
Departments of Statistics & Actuarial Science and Health Studies & 
Gerontology
University of Waterloo
jdubin at uwaterloo.ca

_______________________

Message: 44
Date: Thu, 11 May 2006 12:35:52 -0500
From: Hua Ding <hua.ding at vanderbilt.edu>
Subject: [R] time-dependent covariate survival curves
To: r-help at stat.math.ethz.ch
Message-ID: <446375F8.3060102 at vanderbilt.edu>
Content-Type: text/plain; charset=ISO-8859-1; format=flowed

Dear r-users,

Does anyone know how to draw time-dependent survival curves?

Example:

Event outcome: CHD
Time-dependent covariate: NSAID use, which changes over time for each
subject
I'm interested in survival curves stratified by NSAID use.

I'd like to implement Simon & Makuch (1984) method. Is there a R
package/function to draw this graph?


------------------------------------------
Two related papers:

Simon R, Makuch RW. A non-parametric graphical representation of the
relationship between survival and the occurrence of an event:
application to responder versus non-responder bias.  Statistics in
Medicine 1984; 3: 35-44.

Schultz LR, Peterson EL, Breslau N. Graphing survival curve estimates
for time-dependent covariates.  Int'l J of Methods in Psychiatric
Research 2002; 11: 68-74.
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-- Rebecca Ding Biostatistician II School of Medicine Department of 
Biostatistics Vanderbilt University (W)615-343-3878