[R] Meta-Analysis of proportions

Michael Dewey med at aghmed.fsnet.co.uk
Thu Jun 28 19:01:44 CEST 2007


At 09:58 28/06/2007, Chung-hong Chan wrote:
>OpenBUGS should be something related to Bayesian statistics.
>
>You may refer to Chapter 12 of Handbook
>http://cran.r-project.org/doc/vignettes/HSAUR/Ch_meta_analysis.pdf
>It talks about meta-regression.
>
>
>
>On 6/28/07, Monica Malta <momalta at cict.fiocruz.br> wrote:
>>Dear colleagues,
>>
>>I'm conducting a meta-analysis of studies evaluating adherence of 
>>HIV-positive drug users into AIDS treatment, therefore I'm looking 
>>for some advice and syntax suggestion for running the 
>>meta-regression using proportions, not the usual OR/RR frequently 
>>used on RCT studies.

Monica, you have a number of options.
1 - weight each study equally
2 - weight each individual equally
3 - use the usual inverse variance procedure, possibly transforming 
the proportions first
4 - something else I have not though of

You could do 3 using rmeta which is available from CRAN. Programming 
1 or 2 is straightforward.
Of course, you do need to decide which corresponds to your scientific question.


>>Have already searched already several handbooks, R-manuals, mailing 
>>lists, professors, but... not clue at all...
>>
>>Does anyone have already tried this? A colleague of mine recently 
>>published a similar study on JAMA, but he used OpenBUGS - a 
>>software I'm not familiar with...
>>
>>If there is any tip/suggestion for a possible syntax, could someone 
>>send me? I need to finish this paper before my PhD qualify, but I'm 
>>completely stuck...
>>
>>So, any tip will be more than welcome...I will really appreciate it!!!
>>
>>Thanks in advance and congrats on the amazing mailing-list.
>>
>>
>>
>>Bests from Rio de Janeiro, Brazil.
>>
>>Monica
>>
>>
>>
>>
>>
>>Monica Malta
>>Researcher
>>Oswaldo Cruz Foundation - FIOCRUZ
>>Social Science Department - DCS/ENSP
>>Rua Leopoldo Bulhoes, 1480 - room 905
>>Manguinhos
>>Rio de Janeiro - RJ 21041-210
>>Brazil
>>phone +55.21.2598-2715
>>fax +55.21.2598-2779
>>         [[alternative HTML version deleted]]
>>
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>
>
>--
>"The scientists of today think deeply instead of clearly. One must be
>sane to think clearly, but one can think deeply and be quite insane."
>Nikola Tesla
>http://www.macgrass.com
>
>

Michael Dewey
med at aghmed.fsnet.co.uk
http://www.aghmed.fsnet.co.uk/home.html



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