[R] group sequential analysis - stopping for futility

[Bernardo Rangel Tura]

Em Ter, 2008-10-28 às 08:30 -0700, Alice.Pressman at nsmtp.kp.org escreveu:
> Hello - 
> 
> I am wondering if anyone has written some R code to calculate futility 
> bounds for a group sequential analysis of clinical trials data.  The 
> library ldbounds has a function 'bounds'  which calculates the 
> effectiveness stopping bounds for various spending functions,  but it does 
> not appear to do the same for futility (sometimes called the 'inner 
> wedge').
> 
> Thanks for any assistance!
> 
> -Alice


Hi alice, 

I have interest in develop this code with you .

Do you have a paper about this?
-- 
Bernardo Rangel Tura, M.D,MPH,Ph.D
National Institute of Cardiology
Brazil