[R] Global fit analysis

[Bert Gunter]

I suspect you received no reply as no one knows what you mean by
"global fit analysis." If you have some specific technical definition
in mind, provide a reference. Better yet, SEARCH (see CRAN's Task
Views).

If you are merely mis-referring to "goodness of fit" measures, than
all R's modeling functions in all packages provide such measures, this
is a statistics-- not an R -- question, and you need to do some
reading or consult a local statistician, not pester this list further.

Cheers,
Bert

On Tue, Jul 9, 2013 at 11:17 AM, Asan Ramzan <asanramzan at yahoo.com> wrote:
> I sending this again as I forgot to add a subject
>
>
> Hello R-help
>
> Does anyone know if there is a package for global
> fit analysis and if so how to use it.  I am trying to calculate the Kd
> value of a protein interacting with its ligand (When protein interacts
> with ligand this effect a number of residues). The table below
> shows with increasing concentration of ligand changes in three different
>  residues.
>
> Concentration  res1 res2  res3
> 0 0 0  0
> 1.99167E-05 0.012978 0.020862  0.03032
> 3.95847E-05 0.019562 0.032288  0.048266
> 7.82652E-05 0.021842 0.036  0.05521
> 0.000115656 0.025274 0.043862  0.06398
> 0.000151801 0.029896 0.048762  0.075302
> 0.000186741 0.033544 0.053556  0.084334
> 0.000220516 0.035676 0.058964 0.0914
> 0.000274932 0.037834 0.061818  0.097096
> 0.000352021 0.040694 0.066216  0.100024
> 0.000422686 0.04329 0.070414  0.109974
> 0.000552238 0.045482 0.074646  0.116072
> 0.000777155 0.047062 0.07671  0.118722
> 0.0012 0.05345 0.08602 0.130344
>         [[alternative HTML version deleted]]
>
>
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>



-- 

Bert Gunter
Genentech Nonclinical Biostatistics

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