[R] Efficient way of loading files in R

[Deepa]

Hello,

I am using a bioconductor package in R.
The command that I use reads the contents of a file downloaded from a
database and creates an expression object.

The syntax works perfectly fine when the input size is of 10 MB. Whereas,
when the file size is around 40MB the object isn't created.

Is there an efficient way of loading a large input file to create the
expression object?

This is my code,


library(gcrma)
library(limma)
library(biomaRt)
library(GEOquery)
library(Biobase)
require(GEOquery)
require(Biobase)
gseEset1 <- getGEO('GSE53454')[[1]] #filesize 10MB
gseEset2 <- getGEO('GSE76896')[[1]] #file size 40MB

##gseEset2 doesn't load and isn't created

Many thanks

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