[BioC] distribution of genes differentially expressed

[A.J. Rossini]

Phguardiol at aol.com writes:


> I d like to know if there is a package in BioC that can identify genes that 
> are differentially expressed between 2 conditions and  analyze their 
> distribution along the chromosomes to say if their distribution is random or 
> if it has a non random distribution with some sort of clusters in some part 
> of the chromosomes... for instance, a tool that could help to detect 
> translocations, loss or gain of chromosomes from the microarray data...
> thanks

You can do it, but I think you are talking about at least 2 packages,
assuming that you are using annotated gene expression arrays, and you
need to define (and possibly program up) specifically what you mean by
"differential".  There are at least 10 specific definitions, if not
hundreds more possible.

best,
-tony

-- 
A.J. Rossini  rossini at u.washington.edu  http://software.biostat.washington.edu/
Biostatistics, U Washington and Fred Hutchinson Cancer Research Center
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