[BioC] ttest or fold change

Jason Hipp jhipp at wfubmc.edu
Sat Dec 13 16:45:30 MET 2003

I am comparinga relatively homogeneous cell culture to another that has been treated, and am using RMA.  
I only have 3 replicates of each.  Would you recommend a 2 tailed equal variance t test?  
I also thought I read that with such few replicates, a fold change would be better than a t test?
If I get a t test of .0001, and a fold change of 1.2, is this a reliable change using RMA?

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