[BioC] normalize.method="invariantset"

[Hinnerk Boriss]

Hi!

I have two question regarding the invariant set method for
normalization. First, is the algorithm the IDS described by Schadt et
al. (2001)? With any further modifications? Second, what do the warnings
below mean?

Best,
Hinnerk


> HEP.invset <- express(HEP,normalize.method="invariantset")
Background correcting
Normalizing Data
12625 ProbeSets to be processed
.........
Warning messages: 
1: Collapsing to unique x values in: approx(tmp$n.curve$y,
tmp$n.curve$x, xout = intensity(abatch)[,  
2: Collapsing to unique x values in: approx(tmp$n.curve$y,
tmp$n.curve$x, xout = intensity(abatch)[,  
3: Collapsing to unique x values in: approx(tmp$n.curve$y,
tmp$n.curve$x, xout = intensity(abatch)[,