[BioC] Rocke-Lorenzato model or Global Error Model in Bioconductor

Wolfgang Huber huber at ebi.ac.uk
Wed Dec 7 14:51:56 CET 2005

Hi Ruppret,

check the vsn package, its vignette and the references therein. The 
function vsn estimates the parameters of a model that is derived from 
the multiplicative-additive error model, in particular, parameters of 
the glog transformation.


Ruppert Valentino wrote:
> Hello,
> I wonder if anyone knows what is the nearest thing to the Globel Error Model 
> (two-component (Rocke-Lorenzato) error model) in Bioconductor and how to use 
> it.
> I would like to compare the results I got in GeneSpring using the Global 
> Error Model using something similar in Bioconductor but wonder if a pakcage 
> for such model exist, if not is there anything that resemble it?
> Thanks,
> Raphael

Wolfgang Huber
European Bioinformatics Institute
European Molecular Biology Laboratory
Cambridge CB10 1SD
Phone: +44 1223 494642
Fax:   +44 1223 494486
Http:  www.ebi.ac.uk/huber

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