[BioC] Generic Loess Normalization

James W. MacDonald jmacdon at med.umich.edu
Thu Mar 3 15:17:46 CET 2005


Gene Cutler wrote:
> Of the various Bioconductor methods, is there any which performs a 
> fairly generic loess normalization, leaving out fancy stuff like 
> print-tip normalization, etc?
> 
> I'd like to write some code based on this, so I'd like to see a 
> stripped-down example if there is one out there.

You might look at loessFit in the limma package. Much of the heavy 
lifting appears to be done in C, however.

Jim


> 
> Thanks.
> 
> 
> 
> Gene Cutler
> Principal Scientist
> Bioinformatics
> Amgen SF
> 
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-- 
James W. MacDonald
Affymetrix and cDNA Microarray Core
University of Michigan Cancer Center
1500 E. Medical Center Drive
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