[BioC] split arrays

scholz@Ag.arizona.edu scholz at Ag.arizona.edu
Tue Sep 27 13:20:59 CEST 2005


Recently you advised someone with a split set of maize arrays that they could do
their analysis by reading all the A slides into an RGList and normalizing, then
doing the same with the B slides, and then combining the two datasets via
rbind() of the two MAList objects. I have a similar (the same?) set of arrays
and some of the users of these arrays have noted that the A and B slides perform
differently, i.e. more background on the B slide, for whatever reason. Though
I'm not actually convinced this is true, it makes me wonder whether the two
datasets should be combined at all since there may be a "between array set"
source of variation. Am I right to segregate these sets or is there some
overwhelming benefit to combining them? I'm no statistician and would appreciate
your take.



College of Agriculture and Life Sciences Web Mail.

More information about the Bioconductor mailing list