[BioC] detection calls without MM probes
Julien.Roux at unil.ch
Fri Mar 14 14:11:17 CET 2008
When using MAS5 detection calls in affymetrix chips, the assumption is
that the MM probes give a reasonable estimate of background. If we
normalize affy chips with RMA, MM probes are not used.
In similar way, I was wondering if another method was available to
estimate the presence/absence of genes without teh use of MM probes?
I think this would be feasible since RMA estimates the parameters of the
background distribution (bg.parameters), I just don't really know how to
Thanks a lot for your help
Julien Roux, PhD student
Department of Ecology and Evolution
Biophore, University of Lausanne, 1015 Lausanne, Switzerland
tel: +41 21 692 4221 fax: +41 21 692 4165
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