[BioC] limmaGUI - venn-diagram & top-table anomaly?

Keith Satterley keith at wehi.EDU.AU
Wed Sep 9 01:40:44 CEST 2009


Hi Danny,

I've looked into how these functions were coded. They use different 
functions to categorize genes, hence the different numbers. The next 
version of limmaGUI released with R2.10 in October will use similar 
functions. I will email when the developer version is available that 
produces matching results for Venn diagrams and toptables. Thanks for 
pointing this out,

cheers,

Keith

========================
Keith Satterley
limmaGUI maintainer
=======================



D.Levin at warwick.ac.uk wrote:
> Hello,
>
> In limmaGUI, after running a linear model for a single gene & time point
> (mutant vs control), the venn-diagram for differentially expressed genes
> with a 0.001 p-value cut-off gives a different number than the top-table with
> the same cut-off (2600 vs. 791).
>
> I have seen the same thing happen before for multiple time points (when
> the venn-diagram is more relevant)
>
> Any ideas what is going on?
>
> Thanks
>
> Danny
>
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