[BioC] compare IC50 in DRC package

Hervé Pagès hpages at fhcrc.org
Thu Aug 11 23:33:42 CEST 2011


On 11-08-10 02:04 AM, andrea.grilli at ior.it wrote:
> Hi to all,
> I have 4 cell lines, 2 in group A and 2 in group B, for which I
> calculated IC50.
> I want to know if there is some difference between the 2 groups: a
> simple t-test seems to me a not correct test for this case. Do you know
> if exists in DRC package (or in any other package) a more specific test
> and how to perform it?

I don't know anything about those tests but just wanted to mention that
there is no DRC package in Bioconductor (there is a drc pkg on CRAN
though...)

> I checked in manual but I didn't find a solution.

It would probably be helpful to know which manual you checked exactly.

Cheers,
H.

>
> Thanks in advance,
> Andrea
>
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-- 
Hervé Pagès

Program in Computational Biology
Division of Public Health Sciences
Fred Hutchinson Cancer Research Center
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