[BioC] GEO: Finding up- and down-regulated genes in GDS records

Ovokeraye Achinike-Oduaran ovokeraye at gmail.com
Sun Sep 18 13:53:02 CEST 2011


Thanks Sean. I just realized that I hadn't acknowledged your response.
My apologies.

Thanks again.

Avoks

On Fri, Sep 16, 2011 at 6:31 PM, Sean Davis <sdavis2 at mail.nih.gov> wrote:
> There is not a way to get this information from R or from the website,
> for that matter.  That said, you can download the data and perform
> local calculations using R.  See the GEOquery package for the
> "download" part and the limma package, for example, for the analysis
> side of things.
>
> Sean
>
>
> On Fri, Sep 16, 2011 at 9:59 AM, Ovokeraye Achinike-Oduaran
> <ovokeraye at gmail.com> wrote:
>> Hi,
>>
>> I don’t even know if this is remotely possible but I just thought I
>> should take a chance.  On the GDS record pages in GEO, there is an
>> analysis tools button. Clicking on this gives the option of finding
>> genes that are up/down for the condition in the dataset, I believe.
>> The result however does not indicate which is up or down
>> regulated...at least I can’t seem to find where it shows that. Is it
>> possible to somehow retrieve this information on up- and down-
>> regulated genes in with R?
>>
>> Thanks.
>>
>> Avoks
>>
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>



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