[BioC] GEO: Finding up- and down-regulated genes in GDS records

Sean Davis sdavis2 at mail.nih.gov
Fri Sep 16 18:31:29 CEST 2011


There is not a way to get this information from R or from the website,
for that matter.  That said, you can download the data and perform
local calculations using R.  See the GEOquery package for the
"download" part and the limma package, for example, for the analysis
side of things.

Sean


On Fri, Sep 16, 2011 at 9:59 AM, Ovokeraye Achinike-Oduaran
<ovokeraye at gmail.com> wrote:
> Hi,
>
> I don’t even know if this is remotely possible but I just thought I
> should take a chance.  On the GDS record pages in GEO, there is an
> analysis tools button. Clicking on this gives the option of finding
> genes that are up/down for the condition in the dataset, I believe.
> The result however does not indicate which is up or down
> regulated...at least I can’t seem to find where it shows that. Is it
> possible to somehow retrieve this information on up- and down-
> regulated genes in with R?
>
> Thanks.
>
> Avoks
>
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