[BioC] A bug in either KEGG or KEGGSOAP?

Diego Diez diego10ruiz at gmail.com
Wed Jan 25 03:53:17 CET 2012


Hi SangChul

You may get some insight into what the problem is if you contact the
KEGG stuff at:

http://www.genome.jp/feedback/

then specify "KEGG API" in the options. Since there has been a lot of
structural changes in KEGG recently it may be a transient problem.

Diego

On Tue, Jan 24, 2012 at 6:24 PM, Carlson, Marc R <mcarlson at fhcrc.org> wrote:
> Hi SangChui,
>
> The discrepancy you are seeing is hard to explain from the bioconductor code for this function.  The KEGGSOAP package is basically parsing data from a service on the KEGG site.  The only code in the actual KEGGSOAP package is what is needed to talk to the SOAP services provided by KEGG.  So the fact that the function is working and producing an output means that it is unlikely that there is a bug in KEGGSOAP.  There is nothing in the KEGGSOAP package that tries to limit the number or pathways returned.  So it seems that the most likely cause for this kind of discrepancy is that the SOAP service and the KEGG website are somehow out of sync with each other.
>
>
>  Marc
>
>
> ----- Original Message -----
> From: "Sang Chul Choi" <schoi at cornell.edu>
> To: bioconductor at r-project.org
> Sent: Monday, January 23, 2012 11:59:21 AM
> Subject: [BioC] A bug in either KEGG or KEGGSOAP?
>
> Hi,
>
> I am wondering if this is an old bug eighter in KEGG or KEGGSOAP (v1.28.0).  The version of R is R version 2.14.1 (2011-12-22).
>
> I installed KEGGSOAP, and tried to list pathways.  While list.pathways lists 44, the KEGG website shows 88 pathways.
>
> http://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+gn:T00100
> http://www.genome.jp/dbget-bin/www_bget?gn:T00100
>
> Thank you,
>
> SangChul
>
>> source("http://www.bioconductor.org/biocLite.R")
>> biocLite("KEGGSOAP")
>> library(KEGGSOAP)
>> y <- list.pathways("smu")
>> length(y)
> [1] 44
>
>> sessionInfo()
> R version 2.14.1 (2011-12-22)
> Platform: x86_64-apple-darwin9.8.0/x86_64 (64-bit)
>
> locale:
> [1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8
>
> attached base packages:
> [1] stats     graphics  grDevices utils     datasets  methods   base
>
> other attached packages:
>  [1] KEGGSOAP_1.28.0        BiocInstaller_1.2.1    goseq_1.6.0
>  [4] BiasedUrn_1.04         geneLenDataBase_0.99.8 RColorBrewer_1.0-5
>  [7] maptools_0.8-14        sp_0.9-93              foreign_0.8-48
> [10] xtable_1.6-0           DESeq_1.6.1            locfit_1.5-6
> [13] lattice_0.20-0         akima_0.5-7            Biobase_2.14.0
> [16] plotrix_3.3-3          GenomicRanges_1.6.4    IRanges_1.12.5
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