[BioC] How to use 'ebayes' for small samples?

[Paul Geeleher]

eBayes() is for use with microarray data, i.e. when you are measuring
the expression of many genes, as it works by borrowing information
across all genes. If you are measuring the expression of just one gene
(assuming the measurement wasn't derived from a microarray), you
should use a t.test().

Paul.

On Tue, Apr 16, 2013 at 3:11 AM, Gundala Viswanath <gundalav at gmail.com> wrote:
> I have the following expression data
> from test and control, each contain two sample.
>
> test <- c(3922.89022881,4235.76026274)
> control <- c(3694.11962861,4369.97835686)
>
>
> I want to compute P-value using , to see if
> they are differentially expressed, using
> "ebayes"  http://rss.acs.unt.edu/Rdoc/library/limma/html/ebayes.html'
>
> What's the way to go about it?
> It's not clear from the help file.
>
>
>
> - G.V.
>
>         [[alternative HTML version deleted]]
>
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Dr. Paul Geeleher, PhD (Bioinformatics)
Section of Hematology-Oncology
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