[BioC] Can logFC be used to determine effect size?

Jack [guest] guest at bioconductor.org
Fri Aug 9 11:02:31 CEST 2013


Hello,
I am trying to work out the meaning of logFC in the toptable from limma package. Some sources say that it is the log2 of FC and others say that it is not.

Is this value the actual difference in averages of cases and controls (and as such can it be used to determine effect size)?

Regards,
Jack

 -- output of sessionInfo(): 

R version 2.15.2 Patched (2012-11-28 r61176)

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