[BioC] statistical test for time course data

[Steve Lianoglou]

Hi Juliet,


On Mon, Feb 11, 2013 at 10:39 PM, Juliet Hannah <juliet.hannah at gmail.com> wrote:
> Hi Gordon,
>
> I've been curious about this as well. Can limma model the following
> situation?
[snip]

I think you'll find a thread that appeared a bit after the one you are
replying to:

http://thread.gmane.org/gmane.science.biology.informatics.conductor/46188

If you look in Section 8.6 of the limmaUserGuide (in development):

http://bioconductor.org/packages/2.12/bioc/vignettes/limma/inst/doc/usersguide.pdf

You'll find a section on time course analysis. 8.6.2, in particular,
uses splines.

HTH,
-steve

-- 
Steve Lianoglou
Graduate Student: Computational Systems Biology
 | Memorial Sloan-Kettering Cancer Center
 | Weill Medical College of Cornell University
Contact Info: http://cbio.mskcc.org/~lianos/contact