[BioC] about coverage profile comparison

[rcaloger]

Hi,
I am investigating the interplay of different isoforms, in alternative 
splicing differential expression.
I would like to compare coverage profiles of the same isoform with or 
without the presence of the other isoforms, there is any tool, in 
bioconductor, that allows manipulation of coverage profile, e.g. 
subtraction of a profile to an other or comparison between different 
coverage profiles?
Cheers
Raffaele

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Prof. Raffaele A. Calogero
Bioinformatics and Genomics Unit
MBC Centro di Biotecnologie Molecolari
Via Nizza 52, Torino 10126
tel.   ++39 0116706457
Fax    ++39 0112366457
Mobile ++39 3333827080
email: raffaele.calogero at unito.it
        raffaele[dot]calogero[at]gmail[dot]com
www:   http://www.bioinformatica.unito.it