[R] PFIM 3.2

[Naser Jamil]

Dear R-user,
I'm having some difficulty with working PFIM 3.2, a package for
implementing population PK/PD in R. I wish to evaluate the determinant of
Fisher information matrix each time with successive dose from a pre defined
sequence of doses and want to store those values in a vector. It's
important to note that in my 'stdin.r' file, dose<-c(u) and each time u is
to be replaced as I said. I think a quick look on the following R codes
will give a more clearer picture of the objective:

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directory<-"F:\\PFIM3.2_examples\\experiment"  # working directory
directory.program<-"F:\\PFIM3.2.2\\PFIM3.2.2\\PFIM3.2.2\\Program"  #
program directory

true.dose<-seq(0,10,0.5) # predefined sequence of doses
deter=c()   # to store determinant values
for (i in 1:length(true.dose)  {
u<-true.dose[i]
source("F:\\PFIM3.2.2\\PFIM3.2.2\\PFIM3.2.2\\Program\\LibraryPK.r")
source("F:\\PFIM3.2_examples\\experiment\\model.r")
source("F:\\PFIM3.2_examples\\experiment\\stdin.r")
source("F:\\PFIM3.2_examples\\experiment\\PFIM3.2.r")
res<-PFIM()
deter[i]<-res$determinant
}

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But it's not working anyway and of course showing some error messages.

I have attached the the associated files.

Any suggestion in this regard will help me a lot.


Thank you very much for the patience!


Regards,

Jamil.