[BioC] normalization and analysis of connected designs

Ramon Diaz-Uriarte rdiaz at cnio.es
Wed Jul 2 12:13:18 MEST 2003


> > add the ratios"? Is there something obvious I am missing?
>
> Yes, you have misunderstood the point of the normalization step, which is
> to bring the log-ratios back to the scale on which the log-ratios have the
> expected linear relationships. If the log-ratios already obeyed the
> relationships such as D-A = AB+BC+CD straight off the arrays then we
> wouldn't normalize!

Oooops, I shouldn't have missed that! Thank you very much for your answer.

Best,

Ramón



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