[BioC] vsn in BioConductor 1.2

[White, Charles E WRAIR-Wash DC]

Could someone help me interpret (develop an action plan to correct ...) the
error message that follows?

 

Thanks. 

 

> Monkey.sub<-Monkey.expr[!is.na(Monkey.matrix[,1]),1]

> Monkey.sub

Expression Set (exprSet) with 

      13838 genes

      1 samples

             phenoData object with 6 variables and 1 cases

       varLabels

            : Slide

            : FileName

            : Cy3

            : Cy5

            : date

            : Comments

> Monkey.sub<-exprs(Monkey.expr[!is.na(Monkey.matrix[,1]),1])

> Monkey.vsn<-vsn(Monkey.sub)

vsn is working on a 13838 x 1 matrix, with lts.quantile=0.5; please wait for
11 dots:

.Error in optim(par = p0, fn = ll, gr = grll, method = "L-BFGS-B", control =
control,  : 

      L-BFGS-B needs finite values of fn


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