[BioC] PLIER: two questions

[Ariel Chernomoretz]

Hi,
Just a couple of questions about plier

a) With justPlier it is possible to specify as an input vector the replicate 
structure of the batch we want to analyze ('replicate' input option).
Can anybody tell me how this information is used by the algorithm? In fact, 
can anybody point me to some technical references on how plier works?   

b) I found that the 64-bit compiled version of plier  presents some stability 
issues (i.e. it crashes). A couple of month ago Adai posted a message 
(http://files.protsuggest.org/biocond/html/9034.html)  saying that
he solved a similar (I hope) problem. 
So, Adai, Crispin, anybody, could you please point me in the right direction 
in order to make plier run under my 64-bit Opteron?


Thank you

Ariel./



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Ariel Chernomoretz, Ph.D.
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