[BioC] cross-species affy analysis

Sean Davis sdavis2 at mail.nih.gov
Mon Apr 3 13:36:19 CEST 2006




On 4/3/06 5:28 AM, "Dario Greco" <dario.greco at helsinki.fi> wrote:

> hello list,
> 
> I am approaching a meta-analysis task where I have to compare Affy data
> from human, mouse and rat chipsets.
> 
> I have seen some interesting things in Gregoryev et al. GenomeBiology
> 2004. There, the authors have used external tools (RESOURCERER and EGO) to
> define the ortholog gene sets between several pairs of Affy GeneChips.
> 
> I was wondering if since then, any internal BioConductor tool has been
> developed (or it is in the plans of BioC developers for the future).

Look at the biomaRt package and particularly at the getXref function.  Also,
you could look at using the HOMOLOGY metadata package.

Sean



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