[R] Time Dependent Cox Model

quaildoc just.struttin at gmail.com
Wed Oct 14 21:19:20 CEST 2009


Some suggested that go into more detail on what I wanted to accomplish and
the rest of my code.  I want to accomplish exactly what Fox did in this
article( http://www.nabble.com/file/p25897307/appendix-cox-regression.pdf
appendix-cox-regression.pdf ) (starting with page 7), except using "habitat"
instead of employment. I want habitat to be a time dep. covariate and it
varys by day.

I read in my data as the csv. file, and one major difference in the data set
Fox used and min is I have a DaysatRisk column instead of the "week" the
person went back to jail. This I think is the root of my problem calculating
the proper death.time.  The death.time column should be 1s and 0s that
corresponds to the day the animal died. 

Thanks in advance,



surv<-read.csv("Survival_master2.csv", header = TRUE)

sum(!is.na(surv[,16:726]))

surv2<-matrix(0,12329,19)
colnames(surv2)<-c('start', 'stop', 'death.time',
names(surv)[1:15],'habitat')
row<-0 # set record counter to 0
    for (i in 1:nrow(surv)) { # loop over individuals
        for (j in 16:726) { # loop over 52 weeks
          if (is.na(surv[i, j])) next # skip missing data
          else {
            row <- row + 1 # increment row counter
            start <- j - 11 # start time (previous week)
            stop <- start + 1 # stop time (current week)
            death.time <- if (stop == surv[i, 4] && surv[i, 5] ==1) 1 else 0
                   # construct record:
            surv2[row,] <- c(start, stop, death.time, unlist(surv[i, c(1:15,
j)]))
            }
        }
   }
surv2<-as.data.frame(surv2)
remove(i,j,row,start,stop,death.time)

surv2[1:15,]

test<-coxph(Surv(start,stop,death.time)~habitat, data=surv2)


JorisMeys wrote:
> 
> Well,
> 
> it might be wise to elaborate a bit more about the variables and what
> exactly you want e.g. death-time to be. I'd interprete it as time of
> death, but the fact that it is 0/1, means it is a logical (?) binary
> variable of some sort.
> 
> Please ask your question in such a way that somebody who doesn't know
> the dataset and your research, can still understand what is inside the
> dataset and what exactly you're trying to obtain.
> 
> I'd also suggest to add the command to read in the data. I don't have
> the time to spend looking around how exactly I can read in the dataset
> in such a way it fits what you have in your workspace.
> 
> Cheers
> Joris
> 
> On Wed, Oct 14, 2009 at 5:37 PM, quaildoc <just.struttin at gmail.com> wrote:
>>
>> Does anyone have suggestions? Thanks!
>>
>> quaildoc wrote:
>>>
>>> I am having trouble formatting some survival data to use in a time
>>> dependent cox model. My time dep. variable is habitat and I have it
>>> recorded for every day (with some NAs).  I think it is working properly
>>> except for calculating the death.time. This column should be 1s or 0s
>>> and
>>> as I have it only produces 0s.  Any help will be greatly appreciated.
>>>
>>>
>>>  http://www.nabble.com/file/p25881478/Survival_master2.csv
>>> Survival_master2.csv
>>>
>>>
>>>
>>>  Here is my code:
>>> sum(!is.na(surv[,16:726]))
>>>
>>> surv2<-matrix(0,12329,19)
>>> colnames(surv2)<-c('start', 'stop', 'death.time',
>>> names(surv)[1:15],'habitat')
>>> row<-0 # set record counter to 0
>>>     for (i in 1:nrow(surv)) { # loop over individuals
>>>         for (j in 16:726) { # loop over 726 days
>>>           if (is.na(surv[i, j])) next # skip missing data
>>>           else {
>>>             row <- row + 1 # increment row counter
>>>             start <- j - 11 # start time (previous day)
>>>             stop <- start + 1 # stop time (day)
>>>             death.time <- if (stop == surv[i, 4] && surv[i, 5] ==1) 1
>>> else
>>> 0
>>>                    # construct record:
>>>             surv2[row,] <- c(start, stop, death.time, unlist(surv[i,
>>> c(1:15, j)]))
>>>             }
>>>         }
>>>    }
>>> surv2<-as.data.frame(surv2)
>>>
>>
>> --
>> View this message in context:
>> http://www.nabble.com/Time-Dependent-Cox-Model-tp25881478p25893488.html
>> Sent from the R help mailing list archive at Nabble.com.
>>
>> ______________________________________________
>> R-help at r-project.org mailing list
>> https://stat.ethz.ch/mailman/listinfo/r-help
>> PLEASE do read the posting guide
>> http://www.R-project.org/posting-guide.html
>> and provide commented, minimal, self-contained, reproducible code.
>>
> 
> ______________________________________________
> R-help at r-project.org mailing list
> https://stat.ethz.ch/mailman/listinfo/r-help
> PLEASE do read the posting guide
> http://www.R-project.org/posting-guide.html
> and provide commented, minimal, self-contained, reproducible code.
> 
> 

-- 
View this message in context: http://www.nabble.com/Time-Dependent-Cox-Model-tp25881478p25897307.html
Sent from the R help mailing list archive at Nabble.com.




More information about the R-help mailing list