[BioC] Basic question re: multiple testing

[Claire Wilson]

Dear all,

Apologies if this is slightly off-topic/bit basic! With respects to multiple testing, if you apply it does it change the actual order of significance, i.e. are your top 10 most significantly changing genes the same when you perform a t-test with multiple testing and when you apply a t-test without multiple testing?

Many thanks in advance

Claire

--
Claire Wilson   
Bioinformatics group  
Paterson Institute for Cancer Research  
Christies Hospital NHS Trust  
Wilmslow Road,  
Withington  
Manchester  
M20 4BX  
tel: +44 (0)161 446 8218  
url: http://bioinf.picr.man.ac.uk/
 
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